Title : Transcriptional regulation of phospholipid biosynthesis is linked to fatty acid metabolism by an acyl-CoA-binding-protein-dependent mechanism in Saccharomyces cerevisiae.

Pub. Date : 2007 Oct 15

PMID : 17593018






2 Functional Relationships(s)
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1 In the present study, we show that transcription of the INO1 gene, which encodes inositol-3-phosphate synthase, cannot be fully repressed by inositol and choline, and UAS(INO1) (inositol-sensitive upstream activating sequence)-driven transcription is enhanced in Acb1p-depleted cells. Inositol long-chain fatty acid transporter ACB1 Saccharomyces cerevisiae S288C
2 In addition, the reduction in inositol-mediated repression of INO1 transcription observed after depletion of Acb1p appeared to be independent of the transcriptional repressor, Opi1p. Inositol long-chain fatty acid transporter ACB1 Saccharomyces cerevisiae S288C