Title : Nuclear protein TIA-1 regulates COL2A1 alternative splicing and interacts with precursor mRNA and genomic DNA.

Pub. Date : 2007 Aug 17

PMID : 17580305






1 Functional Relationships(s)
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1 Utilizing a mini-gene consisting of part of the type II procollagen gene (COL2A1), we show that TIA-1 interacts with a conserved AU-rich cis element in COL2A1 intron 2 and modulates alternative splicing of exon 2. Gold TIA1 cytotoxic granule associated RNA binding protein Homo sapiens