Title : Sorafenib inhibits the angiogenesis and growth of orthotopic anaplastic thyroid carcinoma xenografts in nude mice.

Pub. Date : 2007 Jun

PMID : 17575107






1 Functional Relationships(s)
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1 We hypothesized that sorafenib, a multikinase inhibitor of the BRaf, vascular endothelial growth factor receptor-2, and platelet-derived growth factor receptor-beta kinase, would decrease tumor growth and angiogenesis in an orthotopic model of ATC. Sorafenib kinase insert domain protein receptor Mus musculus