Title : Depolarization-induced, glutamate receptor-mediated, and transactivation-dependent extracellular-signal regulated kinase phosphorylation in cultured cerebellar granule neurons.

Pub. Date : 2007 Jun 29

PMID : 17544586






1 Functional Relationships(s)
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1 Both increases in ERK1/2 phosphorylation are also inhibited by GM 6001 (a metalloproteinase inhibitor, preventing "shedding" of growth factors), by AG 1478 (a receptor tyrosine kinase inhibitor, preventing epidermal growth factor [EGF] receptor activation), and also partly by heparin (inactivating heparin-binding epidermal growth factor [HB-EGF]), suggesting transactivation of epidermal growth factor receptors (EGFR). RTKI cpd mitogen-activated protein kinase 3 Mus musculus