Title : Persistent airway inflammation and bronchial hyperresponsiveness in patients with totally controlled asthma.

Pub. Date : 2008 Apr

PMID : 17537187






2 Functional Relationships(s)
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1 METHODS: We assessed the number of eosinophil and the levels of eosinophil cationic protein (ECP) and interleukin (IL)-5 in induced sputum and bronchial responsiveness to methacholine in 76 patients with totally controlled asthma in comparison with 30 current untreated asthmatics and 20 healthy subjects. Methacholine Chloride interleukin 5 Homo sapiens
2 In the total control group, number of eosinophil and the levels of ECP and IL-5 in induced sputum of patients with negative methacholine challenge test were significantly lower than those in subjects with positive methacholine challenge test (p < 0.001), whereas sputum number of eosinophil and the levels of ECP and IL-5 in patients with negative methacholine challenge test and those of healthy subjects were similar (p > 0.05). Methacholine Chloride interleukin 5 Homo sapiens