Title : BubR1 deficiency results in enhanced activation of MEK and ERKs upon microtubule stresses.

Pub. Date : 2007 Jun

PMID : 17531083






1 Functional Relationships(s)
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1 Specifically, treatment with nocodazole and paclitaxel resulted in hyper-activation of ERKs and MEK in BubR1(+/-) murine embryonic fibroblasts (MEF) compared to that of wild-type MEFs. Nocodazole BUB1B, mitotic checkpoint serine/threonine kinase Mus musculus