Pub. Date : 2007 Jun
PMID : 17526834
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cloning and characterization of the genes encoding the high-affinity iron-uptake protein complex Fet3/Ftr1 in the basidiomycete Phanerochaete chrysosporium. | Iron | high-affinity iron permease FTR1 | Saccharomyces cerevisiae S288C |
| 2 | This enzyme shows biochemical and structural similarities with the yeast Fet3p, a type I membrane glycoprotein that efficiently oxidizes Fe(II) to Fe(III) for its subsequent transport to the intracellular compartment by the iron permease Ftr1p. | Iron | high-affinity iron permease FTR1 | Saccharomyces cerevisiae S288C |
| 3 | Northern hybridization studies showed that the mRNA levels of both genes are reduced upon supplementation of the growth medium with iron, supporting the functional coupling of Fet3 and Ftr1 proteins in vivo. | Iron | high-affinity iron permease FTR1 | Saccharomyces cerevisiae S288C |