Title : NP031112, a thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders.

Pub. Date : 2007 May 23

PMID : 17522320






1 Functional Relationships(s)
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1 A well characterized animal model of brain damage involves administration of kainic acid, which causes limbic seizure activity and subsequent neuronal death, especially in the CA1 and CA3 pyramidal cells and interneurons in the hilus of the hippocampus. Kainic Acid carbonic anhydrase 1 Rattus norvegicus