Title : Leptin induces inflammation-related genes in RINm5F insulinoma cells.

Pub. Date : 2007 May 23

PMID : 17521427






1 Functional Relationships(s)
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1 Experiments with LEPRb point mutants revealed that the upregulation of the inflammation-related genes depended on the presence of tyrosine-1138 which mediates the activation of the transcription factors STAT1 and STAT3. Tyrosine signal transducer and activator of transcription 3 Rattus norvegicus