Pub. Date : 2007 Dec 1
PMID : 17516501
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Development and iron-dependent expression of hephaestin in different brain regions of rats. | Iron | hephaestin | Rattus norvegicus |
| 2 | It has been suggested that Hephaestin (Heph), a newly discovered ceruloplasmin homologue, is necessary for iron egress from the enterocytes into circulation via interacting with ferroportin1 (FP1). | Iron | hephaestin | Rattus norvegicus |
| 3 | It has been suggested that Hephaestin (Heph), a newly discovered ceruloplasmin homologue, is necessary for iron egress from the enterocytes into circulation via interacting with ferroportin1 (FP1). | Iron | hephaestin | Rattus norvegicus |
| 4 | Based on the putative function of Heph, and the similarity between the process of iron transport in the enterocytes and that in the blood-brain barrier (BBB) cells, it has also been proposed that Heph plays a similar role in exporting iron from the BBB cells and other brain cells as it works in the enterocytes via interacting with FP1. | Iron | hephaestin | Rattus norvegicus |
| 5 | Based on the putative function of Heph, and the similarity between the process of iron transport in the enterocytes and that in the blood-brain barrier (BBB) cells, it has also been proposed that Heph plays a similar role in exporting iron from the BBB cells and other brain cells as it works in the enterocytes via interacting with FP1. | Iron | hephaestin | Rattus norvegicus |
| 6 | The findings also showed that both the development and iron status have a significant effect on Heph expression and the effects of iron status are regionally specific. | Iron | hephaestin | Rattus norvegicus |
| 7 | It was also suggested that Heph expression is probably regulated at the transcriptional level by the development and iron in these brain regions. | Iron | hephaestin | Rattus norvegicus |
| 8 | These findings, together with other published data, support a putative role of Heph in the iron metabolism in the brain. | Iron | hephaestin | Rattus norvegicus |