Pub. Date : 2007 Jul
PMID : 17510468
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP26 inhibitor R115866 increases retinoid signaling in intimal smooth muscle cells. | Retinoids | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 2 | Thus, an alternative approach to exogenous retinoid administration could be to increase the intracellular level of all-trans retinoic acid by blocking CYP26-mediated degradation of retinoids. | Retinoids | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 3 | Thus, an alternative approach to exogenous retinoid administration could be to increase the intracellular level of all-trans retinoic acid by blocking CYP26-mediated degradation of retinoids. | Retinoids | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 4 | CONCLUSIONS: Blocking of the CYP26-mediated catabolism mimics the effects of exogenously administrated active retinoids on intimal SMCs. | Retinoids | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |