Title : Targeting MEK induces myeloma-cell cytotoxicity and inhibits osteoclastogenesis.

Pub. Date : 2007 Sep 1

PMID : 17510321






1 Functional Relationships(s)
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1 Importantly, AZD6244 (200 nM) induces apoptosis in patient MM cells, even in the presence of exogenous interleukin-6 or BMSCs associated with triggering of caspase 3 activity. AZD 6244 caspase 3 Homo sapiens