Title : Over-expressing GLT1 in a gpd2Delta mutant of Saccharomyces cerevisiae to improve ethanol production.

Pub. Date : 2007 Jul

PMID : 17505823






2 Functional Relationships(s)
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1 We constructed two recombinant strains of Saccharomyces cerevisiae in which the GPD2 gene was deleted using a one-step gene replacement method to minimize formation of glycerol and improve ethanol production. Glycerol glycerol-3-phosphate dehydrogenase (NAD(+)) GPD2 Saccharomyces cerevisiae S288C
2 Although gene GPD2 is responsible for the glycerol synthesis, the mutant KAM-13, in which glycerol formation was substantially reduced, was able to cope and maintain osmoregulation and redox balance and have increased ethanol production under anaerobic fermentations. Glycerol glycerol-3-phosphate dehydrogenase (NAD(+)) GPD2 Saccharomyces cerevisiae S288C