Title : Amide derivatives of 2,3-diarylacrylophenone as estrogen receptor binding ligands.

Pub. Date : 2007 May

PMID : 17504195






1 Functional Relationships(s)
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1 In order to throw light on their SAR, In silico docking of the acrylophenone derivatives in the ligand binding site of the ERalpha and their comparison with pure steroidal estrogen antagonist ICI-164,384 and the non-steroidal antiestrogen raloxifene, was carried out. 3-oxo-3-phenylpropene sarcosine dehydrogenase Homo sapiens