Pub. Date : 2007 Aug 1
PMID : 17499231
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Molecular interaction between caveolin-1 and ABCA1 on high-density lipoprotein-mediated cholesterol efflux in aortic endothelial cells. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
2 | OBJECTIVE: Caveolin-1 and ATP-binding cassette transporter A1 (ABCA1) are proteins that are involved in cellular cholesterol efflux. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
3 | OBJECTIVE: Caveolin-1 and ATP-binding cassette transporter A1 (ABCA1) are proteins that are involved in cellular cholesterol efflux. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
4 | In this study, we analyzed the relationships between caveolin-1 and ABCA1 on high-density lipoprotein (HDL)-mediated cholesterol efflux in rat aortic endothelial cells. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
5 | Immunoelectron microscopy demonstrated that caveolin-1 colocalized with ABCA1 in the caveolae and in the cytoplasmic vesicles; it was also found that caveolin-1 and ABCA1 colocalized with cellular cholesterol by immunofluorescence microscopy. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |
6 | CONCLUSIONS: The molecular interaction between caveolin-1 and ABCA1 is associated with the HDL-mediated cholesterol efflux pathway in aortic endothelial cells. | Cholesterol | ATP binding cassette subfamily A member 1 | Rattus norvegicus |