Pub. Date : 2007 Apr-Jun
PMID : 17485788
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AIM: To examine the anti-inflammatory effects of green tea polyphenols on oxLDL-mediated TNFalpha expression and NF-KB activation in the human umbilical vein endothelial cells (HUVECs). | Polyphenols | tumor necrosis factor | Homo sapiens |
| 2 | METHODS: We postulate that green tea polyphenols regulate TNF-alpha gene expression by modulating NF-KB activation through their inhibition effect on IKB Kinase (IKK) activity and as scavenger of free radicals. | Polyphenols | tumor necrosis factor | Homo sapiens |
| 3 | Pretreatment of green tea polyphenols reduced oxLDL-induced production of proinflammatory cytokine TNF-alpha and NF-KB activation in dose dependent manner (p < 0.05). | Polyphenols | tumor necrosis factor | Homo sapiens |
| 4 | The effect of green tea polyphenols on TNF-alpha expression were determined by Mann-Whitney test. | Polyphenols | tumor necrosis factor | Homo sapiens |
| 5 | In this study, green tea polyphenols showed significant effects on the inhibition of TNF-alpha through NF-KB activation pathway in HUVECs with oxidized LDL. | Polyphenols | tumor necrosis factor | Homo sapiens |