Title : Mechanism by which alcohol and wine polyphenols affect coronary heart disease risk.

Pub. Date : 2007 May

PMID : 17478321






2 Functional Relationships(s)
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1 Up-regulation of t-PA gene transcription, through specific alcohol and polyphenol transcription factor binding sites in the t-PA promoter, results in increased in vitro fibrinolysis and in vivo clot lytic activity (using real-time fluorescence [Fl] imaging of Cy5.5-labeled fibrin clot lysis in a mouse model). CY5.5 cyanine dye promotion susceptibility QTL 1 Mus musculus
2 Up-regulation of t-PA gene transcription, through specific alcohol and polyphenol transcription factor binding sites in the t-PA promoter, results in increased in vitro fibrinolysis and in vivo clot lytic activity (using real-time fluorescence [Fl] imaging of Cy5.5-labeled fibrin clot lysis in a mouse model). CY5.5 cyanine dye promotion susceptibility QTL 1 Mus musculus