Pub. Date : 2008 Feb
PMID : 17478073
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vitro, IGF-1 treatment (10(-8)M, 36h) increased progesterone secretion by four-fold in mixed F3 and F4 (F3/4) granulosa cells and by 1.5-fold in F1 granulosa cells. | Progesterone | insulin like growth factor 1 | Gallus gallus |
| 2 | We then studied the effects of AMPK activation by AICAR (5-aminoimidazole-4-carboxamide ribonucleoside), an activator of AMPK, on IGF-1-induced progesterone secretion by F3/4 and F1 granulosa cells. | Progesterone | insulin like growth factor 1 | Gallus gallus |
| 3 | Thus, a variation of energy metabolism through AMPK activation could modulate differently IGF-1-induced progesterone production in F1 and F3/4 granulosa cells. | Progesterone | insulin like growth factor 1 | Gallus gallus |