Title : Bisphenol A induces permanent squamous change in mouse prostatic epithelium.

Pub. Date : 2007 Oct

PMID : 17459086






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Eight-to 9-week-old mice treated for 3 weeks with subcutaneous implants of 0.2-200 mg BPA pellets induced the expression of cytokeratin 10 (CK10) in prostatic basal epithelial cells in a dose-dependent manner. bisphenol A keratin 10 Mus musculus
2 Eight-to 9-week-old mice treated for 3 weeks with subcutaneous implants of 0.2-200 mg BPA pellets induced the expression of cytokeratin 10 (CK10) in prostatic basal epithelial cells in a dose-dependent manner. bisphenol A keratin 10 Mus musculus
3 Fetal exposure to low-dose BPA (20 microg/kg/day) from gestation day (GD) 13 to GD18 induced permanent CK10 expression in basal cells of the adult prostate similar to DES (0.2 microg/kg/day). bisphenol A keratin 10 Mus musculus
4 These results indicate that in mouse, BPA can directly elicit CK10 expression in prostatic epithelium, and that this change can be elicited by doses as low as 20 microg/kg/day. bisphenol A keratin 10 Mus musculus