Title : IGF-I plus E2 induces proliferation via activation of ROS-dependent ERKs and JNKs in human breast carcinoma cells.

Pub. Date : 2007 Sep

PMID : 17458902






2 Functional Relationships(s)
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1 E2/IGF-I-induced proliferation was blocked by chemical inhibitors of ERKs (PD98059) and JNKs (SP600125). 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cystatin 12, pseudogene Homo sapiens
2 An increase in the expression of c-Jun protein was detected in E2/IGF-I-treated MCF-7 cells, and this was inhibited by PD98059 and SP600125. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cystatin 12, pseudogene Homo sapiens