Title : Lycopene binds PDGF-BB and inhibits PDGF-BB-induced intracellular signaling transduction pathway in rat smooth muscle cells.

Pub. Date : 2007 Jun 30

PMID : 17449016






1 Functional Relationships(s)
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1 We found that preincubation of PDGF-BB with lycopene resulted in a marked inhibition on PDGF-BB-induced PDGF receptor-beta (PDGFR-beta), PLCgamma, and ERK1/2 phosphorylation in rat A10 SMCs and primary cultured aortic SMCs. Lycopene platelet derived growth factor receptor beta Rattus norvegicus