Title : Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA.

Pub. Date : 2007 May

PMID : 17443831






3 Functional Relationships(s)
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1 LPA and its analogues are also feedback inhibitors of the enzyme lysophospholipase D (lysoPLD, also known as autotaxin), a central regulator of invasion and metastasis. lysophosphatidic acid ectonucleotide pyrophosphatase/phosphodiesterase 2 Rattus norvegicus
2 LPA and its analogues are also feedback inhibitors of the enzyme lysophospholipase D (lysoPLD, also known as autotaxin), a central regulator of invasion and metastasis. lysophosphatidic acid ectonucleotide pyrophosphatase/phosphodiesterase 2 Rattus norvegicus
3 LPA and its analogues are also feedback inhibitors of the enzyme lysophospholipase D (lysoPLD, also known as autotaxin), a central regulator of invasion and metastasis. lysophosphatidic acid ectonucleotide pyrophosphatase/phosphodiesterase 2 Rattus norvegicus