Title : Hypoxic upregulation of glucose transporters in BeWo choriocarcinoma cells is mediated by hypoxia-inducible factor-1.

Pub. Date : 2007 Jul

PMID : 17442736






2 Functional Relationships(s)
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Protein Name
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1 Reductions in oxygen tension resulted in dose-dependent increases in GLUT1 and GLUT3 expression. Oxygen solute carrier family 2 member 1 Homo sapiens
2 Our results show that GLUTs are upregulated by hypoxia via a HIF-1-mediated pathway in trophoblast cells and suggest that the GLUT response to hypoxia in vivo will be determined not only by low oxygen tension but also by other factors that modulate HIF-1 levels. Oxygen solute carrier family 2 member 1 Homo sapiens