Title : Interdependence of PKC-dependent and PKC-independent pathways for presynaptic plasticity.

Pub. Date : 2007 Apr 19

PMID : 17442248






2 Functional Relationships(s)
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1 First, we confirm that DAG analogs indeed continue to potentiate transmission after PKC inhibition (the Munc13 pathway), but only in neurons that previously experienced DAG analogs, before PKC inhibition started. Diglycerides proline rich transmembrane protein 2 Homo sapiens
2 These data show that activation of both PKC-dependent and -independent pathways (via Munc13) are required for DAG-induced potentiation. Diglycerides proline rich transmembrane protein 2 Homo sapiens