Title : Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion.

Pub. Date : 2007 Apr 15

PMID : 17440088






1 Functional Relationships(s)
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1 Mechanistically, beta(3) integrin interacted physically with the TGF-beta type II receptor (TbetaR-II), leading to its tyrosine phosphorylation by Src and the initiation of oncogenic signaling by TGF-beta. Tyrosine transforming growth factor beta 1 Homo sapiens