Title : Nox1 redox signaling mediates oncogenic Ras-induced disruption of stress fibers and focal adhesions by down-regulating Rho.

Pub. Date : 2007 Jun 15

PMID : 17435218






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This down-regulation involves oxidative inactivation of the low molecular weight protein-tyrosine phosphatase by Nox1-generated ROS and a subsequent elevation in the tyrosine-phosphorylated active form of p190RhoGAP, the direct target of the phosphatase. Tyrosine Rho GTPase activating protein 35 Rattus norvegicus