Title : Conformational change in the active center region of GST P1-1, due to binding of a synthetic conjugate of DXR with GSH, enhanced JNK-mediated apoptosis.

Pub. Date : 2007 Jul

PMID : 17431793

1 Functional Relationships(s)
Compound Name
Protein Name
1 Treatment of cells with a synthetic conjugate of DXR with GSH via glutaraldehyde (GSH-DXR) caused cytochrome c to be released from the mitochondria to the cytosol following potent activation of caspase-3 and -9 by typical DNA fragmentation. Glutathione caspase 3 Homo sapiens