Title : The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.

Pub. Date : 2007 Aug 1

PMID : 17428193






1 Functional Relationships(s)
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1 We employed an in vitro [3H]25OH (25-hydroxycholesterol)-binding assay with purified recombinant proteins as well as live cell photo-cross-linking with [3H]photo-25OH and [3H]photoCH (photo-cholesterol), to investigate sterol binding by the mammalian ORPs. 25-hydroxycholesterol cholesterol 25-hydroxylase Homo sapiens