Pub. Date : 2007 Sep 13
PMID : 17404572
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear Bax. | Arsenic Trioxide | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 2 | The inability of overexpressed p18 Bax to locate to the nucleus, and the As(2)O(3)-induced reduction of p21 Bax in the cytosol, suggest an As(2)O(3)-induced mechanism where p18 Bax gets cleaved and "trapped" in the nucleus. | Arsenic Trioxide | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 3 | The inability of overexpressed p18 Bax to locate to the nucleus, and the As(2)O(3)-induced reduction of p21 Bax in the cytosol, suggest an As(2)O(3)-induced mechanism where p18 Bax gets cleaved and "trapped" in the nucleus. | Arsenic Trioxide | BCL2 associated X, apoptosis regulator | Homo sapiens |