Pub. Date : 2007 Jan
PMID : 17404069
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Resveratrol inhibits IL-1 beta-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro. | Resveratrol | interleukin 1 beta | Homo sapiens |
2 | In this article we investigated whether resveratrol is able to block the effects of IL-1beta, specifically the activation of caspase-3 and subsequent cleavage of poly (ADP-ribose) polymerase (PARP) in human articular chondrocytes. | Resveratrol | interleukin 1 beta | Homo sapiens |
3 | Resveratrol significantly reduced the IL-1beta-induced inhibition of expression of cartilage-specific collagen type II and signal transduction receptor beta1-integrin in a time-dependent manner. | Resveratrol | interleukin 1 beta | Homo sapiens |