Title : Variations in activity and inhibition with pH: the protonated amine is the substrate for monoamine oxidase, but uncharged inhibitors bind better.

Pub. Date : 2007

PMID : 17401535






1 Functional Relationships(s)
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1 The K(i) values for two oxazolidinone inhibitors of MAO-A gave opposite pH-dependence indicating that the uncharged form of each inhibitor bound better than the charged form. Oxazolidinones monoamine oxidase A Homo sapiens