Pub. Date : 2008 Feb 29
PMID : 17399814
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Simvastatin exerts its anti-inflammatory effect in hypercholesterolaemic patients by decreasing the serum levels of monocyte chemoattractant protein-1. | Simvastatin | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | RESULTS: From the inflammatory markers only MCP-1 was decreased significantly (217.4+/-48 versus 177+/-75 pg/ml, p<0.001) after treatment with simvastatin and this reduction was independent of lipid changes. | Simvastatin | C-C motif chemokine ligand 2 | Homo sapiens |
| 3 | CONCLUSION: Simvastatin significantly decreases only MCP-1 levels in hypercholesterolaemic patients suggesting that this molecule is probably a sensitive marker to detect the anti-inflammatory effect of simvastatin in blood. | Simvastatin | C-C motif chemokine ligand 2 | Homo sapiens |
| 4 | CONCLUSION: Simvastatin significantly decreases only MCP-1 levels in hypercholesterolaemic patients suggesting that this molecule is probably a sensitive marker to detect the anti-inflammatory effect of simvastatin in blood. | Simvastatin | C-C motif chemokine ligand 2 | Homo sapiens |