Title : Binding of aflatoxin B1 metabolites in extrahepatic tissues in fetal and infant mice and in adult mice with depleted glutathione levels.

Pub. Date : 1992 Mar 1

PMID : 1737389






1 Functional Relationships(s)
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1 The AFB1 is likely to be bioactivated locally in the extrahepatic tissues; in nonpretreated mice the reactive AFB1 metabolite formed is probably scavenged by GSH via the action of glutathione-S-transferase, whereas in the mice with depleted GSH levels a binding to tissue macromolecules will instead take place. Glutathione hematopoietic prostaglandin D synthase Mus musculus