Title : Nutrient sensing in the mTOR/S6K1 signalling pathway.

Pub. Date : 2007 Apr

PMID : 17371247






2 Functional Relationships(s)
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1 In brief, ectopic expression of hVps34 drives S6K1 activation, but only in the presence of AAs, and this effect is blocked by small interfering RNAs directed against hVps34. Amino Acids phosphatidylinositol 3-kinase catalytic subunit type 3 Homo sapiens
2 Moreover, stimulation of cells with AAs increases hVps34 activity, as indicated by the production of PI3P (phosphatidylinositol 3-phosphate). Amino Acids phosphatidylinositol 3-kinase catalytic subunit type 3 Homo sapiens