Title : Association between IgM against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease.

Pub. Date : 2007 May

PMID : 17363723






3 Functional Relationships(s)
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1 Association between IgM against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease. Aldehydes apolipoprotein B Homo sapiens
2 The aim of this study was to evaluate the relationship between the immune response against one defined oxidized low-density lipoprotein antigen, the aldehyde-modified peptide corresponding amino acids 3136 and 3155 (MDA-p210) in apolipoprotein (apo) B-100, and progression of carotid intima media thickness (IMT). Aldehydes apolipoprotein B Homo sapiens
3 CONCLUSIONS: IgM against the aldehyde-modified peptide corresponding amino acids 3136 and 3155 in apo B-100 is common in subjects with asymptomatic carotid disease, and high levels are associated with a more rapid progression of carotid IMT. Aldehydes apolipoprotein B Homo sapiens