Title : Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.

Pub. Date : 2007 Mar

PMID : 17363505






1 Functional Relationships(s)
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Protein Name
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1 In vitro, the geldanamycin derivate 17-allylamino-17-demethoxygeldanamycin (17-AAG) led to marked reduction in constitutive and inducible activation of extracellular signal-regulated kinase 1/2, Akt, and signal transducer and activator of transcription 3 and decreased nuclear HIF-1alpha protein. tanespimycin N-methylpurine DNA glycosylase Homo sapiens