Pub. Date : 2007 Mar
PMID : 17362743
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The role of toll-like receptor 4 in cisplatin-induced renal injury. | Cisplatin | toll like receptor 4 | Homo sapiens |
| 2 | Herein, we investigated whether the cell toxicity of cisplatin was mediated by toll-like receptor 4 signaling. | Cisplatin | toll like receptor 4 | Homo sapiens |
| 3 | RESULTS: Animals deficient in Toll-like receptor 4 showed less renal dysfunction after cisplatin therapy, which was more evident at later time points. | Cisplatin | toll like receptor 4 | Homo sapiens |
| 4 | CONCLUSIONS: These results suggested that cisplatin-induced renal toxicity is mediated in part though toll-like receptor 4. | Cisplatin | toll like receptor 4 | Homo sapiens |