Title : (-)-Epigallocatechin gallate suppresses endothelin-1-induced interleukin-6 synthesis in osteoblasts: inhibition of p44/p42 MAP kinase activation.

Pub. Date : 2007 Apr 3

PMID : 17350626






2 Functional Relationships(s)
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1 Both the IL-6 synthesis and the phosphorylation of p44/p42 MAP kinase stimulated by 12-O-tetradecanoylphorbol 13-acetate (TPA), a direct activator of PKC, were markedly suppressed by EGCG. Tetradecanoylphorbol Acetate mitogen-activated protein kinase 3 Mus musculus
2 Both the IL-6 synthesis and the phosphorylation of p44/p42 MAP kinase stimulated by 12-O-tetradecanoylphorbol 13-acetate (TPA), a direct activator of PKC, were markedly suppressed by EGCG. Tetradecanoylphorbol Acetate mitogen-activated protein kinase 3 Mus musculus