Pub. Date : 2007 Feb 19
PMID : 17345556
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DEVELOPMENT: A preclinical trial in a knockout mouse showed a decrease in glycosaminoglycans, both in urine and in tissues, following treatment with idursulfase. | Glycosaminoglycans | iduronate 2-sulfatase | Homo sapiens |
| 2 | In a randomised, double-blind, placebo-controlled clinical study in phase I/II conducted in 12 patients with Hunter syndrome, treatment with idursulfase displayed a good safety profile and also a decrease in the excretion of glycosaminoglycans and cases of visceromegaly. | Glycosaminoglycans | iduronate 2-sulfatase | Homo sapiens |