Title : [Effects of arecoline and nicotine on the expression of hTERT in oral keratinocytes].

Pub. Date : 2007 Jan

PMID : 17331439






4 Functional Relationships(s)
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1 [Effects of arecoline and nicotine on the expression of hTERT in oral keratinocytes]. Nicotine telomerase reverse transcriptase Homo sapiens
2 OBJECTIVE: To investigate the effects of arecoline and nicotine on the expression of human telomerase reverse transcriptase (hTERT) mRNA and protein in cultured normal human oral keratinocytes (KC). Nicotine telomerase reverse transcriptase Homo sapiens
3 Nicotine (0.025 g/L) increased hTERT mRNA and protein expression of KC induced by arecoline. Nicotine telomerase reverse transcriptase Homo sapiens
4 hTERT over-expression induced by arecoline and nicotine may play an important role in the malignant transformation of oral submucous fibrosis. Nicotine telomerase reverse transcriptase Homo sapiens