Title : Pharmacophore mapping of selective binding affinity of estrogen modulators through classical and space modeling approaches: exploration of bridged-cyclic compounds with diarylethylene linkage.

Pub. Date : 2007 Mar-Apr

PMID : 17328537






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Supplementing this deduction, critical interfeature distances between hydrogen bond acceptor, hydrophobic, and ring aromatic features along with steric influence are found to primarily influence the ER-subtypes specific binding of this series of compounds. Hydrogen estrogen receptor 1 Homo sapiens