Pub. Date : 2007 Apr
PMID : 17326675
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The binding of both mAbs to their epitopes on the N-domain of ACE is significantly diminished by the presence of the C-domain in the two-domain somatic tissue ACE and further diminished by the presence of sialic acid residues on the surface of blood ACE. | N-Acetylneuraminic Acid | angiotensin I converting enzyme | Homo sapiens |
2 | As a result, the regions of the epitopes for mAb 1G12 and 6A12 on the N-domain, shielded in somatic ACE by the C-domain globule and additionally shielded in blood ACE by sialic acid residues in the oligosaccharide chains localized on Asn289 and Asn416, become unmasked. | N-Acetylneuraminic Acid | angiotensin I converting enzyme | Homo sapiens |
3 | As a result, the regions of the epitopes for mAb 1G12 and 6A12 on the N-domain, shielded in somatic ACE by the C-domain globule and additionally shielded in blood ACE by sialic acid residues in the oligosaccharide chains localized on Asn289 and Asn416, become unmasked. | N-Acetylneuraminic Acid | angiotensin I converting enzyme | Homo sapiens |