Title : Impairment of hepatic Stat-3 activation and reduction of PPARalpha activity in fructose-fed rats.

Pub. Date : 2007 Mar

PMID : 17326204






2 Functional Relationships(s)
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1 Fructose-fed, but not glucose-fed, rats were hyperleptinemic and exhibited increased tyrosine phosphorylation of the signal transducer and activator of transcription-3 (STAT-3) transcription factor, although they did not present a similar increase in the serine phosphorylation of nuclear STAT3. Tyrosine signal transducer and activator of transcription 3 Rattus norvegicus
2 Fructose-fed, but not glucose-fed, rats were hyperleptinemic and exhibited increased tyrosine phosphorylation of the signal transducer and activator of transcription-3 (STAT-3) transcription factor, although they did not present a similar increase in the serine phosphorylation of nuclear STAT3. Tyrosine signal transducer and activator of transcription 3 Rattus norvegicus