Title : Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer.

Pub. Date : 2007 Apr

PMID : 17310282






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Via the reverse of the PDC reaction, NADH and acetyl-CoA reductively acetylate lipoyl group of L2, which binds to the R domain and stimulates PDK2 activity by speeding up ADP dissociation. NAD pyruvate dehydrogenase kinase 2 Homo sapiens