Title : Common structural requirements for heptahelical domain function in class A and class C G protein-coupled receptors.

Pub. Date : 2007 Apr 20

PMID : 17310064






1 Functional Relationships(s)
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1 Indeed, the loss of function resulting from the mutation of the conserved lysine residue into aspartate or glutamate in the TM3 of gamma-aminobutyric acid type B(2) can be partly rescued by mutating the conserved acidic residue of TM6 into either lysine or arginine. Glutamic Acid tropomyosin 3 Homo sapiens