Title : Cytotoxic activity of gemcitabine and correlation with expression profile of drug-related genes in human lymphoid cells.

Pub. Date : 2007 Apr

PMID : 17296311






1 Functional Relationships(s)
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Protein Name
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1 Gemcitabine enters the cell mostly via the human equilibrative nucleoside transporter-1 (hENT1), while drug metabolism occurs by phosphorylation by deoxycytidine kinase (dCK), 5"-nucleotidase (cN-II) and cytidine deaminase (CDA) are the main inactivating enzymes. gemcitabine 5'-nucleotidase ecto Homo sapiens