Title : Resistance to geldanamycin-induced apoptosis in differentiated neuroblastoma SH-SY5Y cells.

Pub. Date : 2007 Mar 6

PMID : 17293044






1 Functional Relationships(s)
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1 Treatment of the cells with all trans retinoic acid (RA) generates a neuron-like, morphological change of differentiation, and results in the activation of ERK and Akt pathways, an inhibition of the nuclear translocation of p53 induced by GA, and induces higher resistance to the GA-induced apoptosis. Tretinoin tumor protein p53 Homo sapiens