Title : Sesquiterpene lactone parthenolide suppresses tumor growth in a xenograft model of renal cell carcinoma by inhibiting the activation of NF-kappaB.

Pub. Date : 2007 Jun 15

PMID : 17290398






1 Functional Relationships(s)
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1 Immunohistochemistry and Western blot analysis showed decreased nuclear localization of NF-kappaB and phosphorylated NF-kappaB protein and subsequently expression of MMP-9, Bcl-xL and Cox-2 in response to parthenolide treatment. parthenolide mitochondrially encoded cytochrome c oxidase II Homo sapiens