Title : Production of stable-isotope-labeled bovine heme and its use to measure heme-iron absorption in children.

Pub. Date : 2007 Feb

PMID : 17284743






23 Functional Relationships(s)
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1 Production of stable-isotope-labeled bovine heme and its use to measure heme-iron absorption in children. Iron HEME Bos taurus
2 Production of stable-isotope-labeled bovine heme and its use to measure heme-iron absorption in children. Iron HEME Bos taurus
3 OBJECTIVE: Our objectives were to produce heme iron enriched in (58)Fe and to use it to study the absorption of heme iron and the effect of iron and zinc intakes on heme-iron absorption in children. Iron HEME Bos taurus
4 OBJECTIVE: Our objectives were to produce heme iron enriched in (58)Fe and to use it to study the absorption of heme iron and the effect of iron and zinc intakes on heme-iron absorption in children. Iron HEME Bos taurus
5 OBJECTIVE: Our objectives were to produce heme iron enriched in (58)Fe and to use it to study the absorption of heme iron and the effect of iron and zinc intakes on heme-iron absorption in children. Iron HEME Bos taurus
6 OBJECTIVE: Our objectives were to produce heme iron enriched in (58)Fe and to use it to study the absorption of heme iron and the effect of iron and zinc intakes on heme-iron absorption in children. Iron HEME Bos taurus
7 OBJECTIVE: Our objectives were to produce heme iron enriched in (58)Fe and to use it to study the absorption of heme iron and the effect of iron and zinc intakes on heme-iron absorption in children. Iron HEME Bos taurus
8 OBJECTIVE: Our objectives were to produce heme iron enriched in (58)Fe and to use it to study the absorption of heme iron and the effect of iron and zinc intakes on heme-iron absorption in children. Iron HEME Bos taurus
9 OBJECTIVE: Our objectives were to produce heme iron enriched in (58)Fe and to use it to study the absorption of heme iron and the effect of iron and zinc intakes on heme-iron absorption in children. Iron HEME Bos taurus
10 OBJECTIVE: Our objectives were to produce heme iron enriched in (58)Fe and to use it to study the absorption of heme iron and the effect of iron and zinc intakes on heme-iron absorption in children. Iron HEME Bos taurus
11 We hypothesized that fractional heme-iron absorption would decrease as heme-iron intake increased and that higher zinc intakes would decrease heme-iron absorption. Iron HEME Bos taurus
12 We hypothesized that fractional heme-iron absorption would decrease as heme-iron intake increased and that higher zinc intakes would decrease heme-iron absorption. Iron HEME Bos taurus
13 We hypothesized that fractional heme-iron absorption would decrease as heme-iron intake increased and that higher zinc intakes would decrease heme-iron absorption. Iron HEME Bos taurus
14 We hypothesized that fractional heme-iron absorption would decrease as heme-iron intake increased and that higher zinc intakes would decrease heme-iron absorption. Iron HEME Bos taurus
15 We hypothesized that fractional heme-iron absorption would decrease as heme-iron intake increased and that higher zinc intakes would decrease heme-iron absorption. Iron HEME Bos taurus
16 We hypothesized that fractional heme-iron absorption would decrease as heme-iron intake increased and that higher zinc intakes would decrease heme-iron absorption. Iron HEME Bos taurus
17 We hypothesized that fractional heme-iron absorption would decrease as heme-iron intake increased and that higher zinc intakes would decrease heme-iron absorption. Iron HEME Bos taurus
18 Fractional iron absorption in children was significantly affected by the intake of heme iron (P = 0.0013) and of zinc (P = 0.0375), but, contrary to expectations, heme-iron absorption was higher at higher zinc intakes. Iron HEME Bos taurus
19 Absolute heme-iron absorption was higher in the group with higher zinc intakes, but only for those with the lowest heme-iron intake (2 mg; P = 0.0147). Iron HEME Bos taurus
20 CONCLUSIONS: Heme iron intrinsically labeled with (58)Fe can be produced at sufficient enrichments for use in human studies. Iron HEME Bos taurus
21 CONCLUSIONS: Heme iron intrinsically labeled with (58)Fe can be produced at sufficient enrichments for use in human studies. Iron HEME Bos taurus
22 In children, heme iron and zinc absorption decrease as the dose of each mineral increases. Iron HEME Bos taurus
23 At lower heme intakes, zinc intakes may increase heme-iron absorption. Iron HEME Bos taurus