Pub. Date : 2007 Mar
PMID : 17276039
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Differential expression of bla(SHV) related to susceptibility to ampicillin in Klebsiella pneumoniae. | Ampicillin | TEM beta-lactamase | Klebsiella pneumoniae |
| 2 | bla(SHV) is thought to be a key beta-lactamase gene responsible for this intrinsic resistance to ampicillin. | Ampicillin | TEM beta-lactamase | Klebsiella pneumoniae |
| 3 | Nevertheless, surveys of clinical strains reveal that some isolates of K. pneumoniae that carry bla(SHV) remain susceptible to ampicillin. | Ampicillin | TEM beta-lactamase | Klebsiella pneumoniae |
| 4 | To explore susceptibility to ampicillin in relation to bla(SHV) in K. pneumoniae, we analysed the existence and transcription of bla(SHV) and determined beta-lactamase activity as well as the susceptibilities to clinically relevant beta-lactams, including ampicillin in 160K. | Ampicillin | TEM beta-lactamase | Klebsiella pneumoniae |
| 5 | The results demonstrate that differential expression of bla(SHV) in clinical isolates of K. pneumoniae can affect susceptibility to ampicillin. | Ampicillin | TEM beta-lactamase | Klebsiella pneumoniae |